Mastering the principles of functioning of living things provides the opportunity to consciously use
them in simpler molecularly organized systems. This is the subject of the biomimetic approach to
solving many chemical problems. If previously biomimetics was understood as ―a part of organic
chemistry that tries to imitate natural reactions and enzymatic processes as a means of increasing the
capabilities of organic chemistry,‖ then later this direction has expanded significantly.
The tasks of biomimetic chemistry are to model biochemical processes at the molecular level and
use the results to obtain ―synthetic‖ enzymes (―synzymes‖), enzyme-like systems that are superior to
natural ones in many properties, the creation of artificial oxygen carriers, synthetic materials of new
technology based on biological substances, modeling coenzymes, ionophores, photoconverting devices,
conductive materials. Enzymes and enzyme-like systems, working on the principle of metalloenzymes
and approaching them in activity and selectivity of action, are used in a variety of areas of practical
human activity: in the food, pharmaceutical, textile industries, in various biotechnological processes, in
the creation of enzymatic analytical systems. Unfortunately, the widespread practical use of native
enzymes is difficult due to their complex production technology, which is associated primarily with
their lability and economic impracticality for use in homogeneous solutions.
These disadvantages can be overcome by using enzymes bound to the carrier in various ways, e.g.
by immobilization. At the same time, the low availability of enzymes, especially their pure preparations,
lability and, as a result, limited use in extreme conditions, create the prerequisites for the creation of
more stable model biocatalytic systems that imitate the active centers of various enzymes. In this regard,
a pressing issue is the creation of new model biocatalysts based on polymer-metal complexes.
Polymer-metal catalysts have been selected for the decomposition of hydrogen peroxide. The
influence of polymer-metallic complexes on the rate of decomposition of hydrogen peroxide has been
studied, and also that iron ions bind to polymers at lower salt concentrations compared to other
transition metals and exhibit greater catalytic activity in the model reaction. The stability during storage
of the complexes and their effectiveness in the decomposition reaction of hydrogen peroxide were
studied.
MODEL REACTION OF HYDROGEN PEROXIDE DECOMPOSITION BY POLYMETAL COMPLEXES
Published December 2023
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Abstract
Language
English
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