Our research was aimed at studying and identifying the features of changes in the health status of senior students in the transition to the updated content of education. The peculiarities of changes in the functional state of the cardiovascular system, adaptive capabilities of the body are revealed. The state of hemodynamics of 10th grade students during the period of adaptation to the updated training format revealed signs of tension in the work of the cardiovascular system of adolescents. During the academic year, the detrained cardiovascular system of adolescents was revealed due to the tension of hypodynamic processes, fatigue of the central nervous system, violations of the regulatory mechanisms of the circulatory system.